Studies Database

Engelke M, Manzer K, Kleuser B, Korting MS. Invitrotrain: Training courses on alternative test methods for the hazard identification of chemicals [abstract]. ALTEX. 2005;22(Special Issue):24

The Invitrotrain project covers the development, validation and – most importantly – the demonstration of in vitro methods for testing of chemicals and prediction of toxicity. In the framework of five training courses established for scientists in the field of toxicology, pharmacology, and chemistry, multiple alternative (non-animal) methods will be educated at the bench and general aspects of the replacement of animal testing by in vitro procedures for the identification of hazardous properties of chemicals will be addressed by lectures. Special focus is placed on the performance of scientifically validated in vitro methods which are accepted in regulatory toxicology and the statistical evaluation of the test results. The aims of the training courses are to provide the attendees with sufficient experience, so that they may apply
the techniques to their own needs and to disseminate the use of in vitro alternative methods.

The training courses will address multiple alternative methods:

- skin corrosivity and phototoxicity

- penetration models

- acute eye toxicity

- reproductive toxicology

- ecotoxicology

The courses will take place biannually (February and July) at the Freie Universität Berlin, Institute of Pharmacy.

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