Studies Database

Hill E and Eskes C. International practical training on in vitro methods [abstract]. ALTEX. 2011;28(Special Issue):224. Abstract 496.

With the recent advancements in the adoption of a considerable number of alternative methods to animal testing by the OECD, and the global harmonization of the world commerce, the importance of providing education on the adopted alternative methods throughout the world is becoming increasingly necessary.

In particular, the specifics of the in vitro test method protocols, the importance of ensuring good laboratory practices, proficiency, reliability and relevance of the method for regulatory purposes, calls for an education preferentially based on practical demonstrations and/or hands-on-training.

Such training is essential to scientists performing in vitro tests, and is also key for regulators to gain the necessary understanding and make critical assessments of the in vitro data. Furthermore, such training could favor standardization of regulatory assessment and decisions on hazard properties of chemicals across the world.

As an example, a practical workshop is currently being organized in Brazil by IIVS, SeCAM, University of Goias and a local organizing committee comprised of representatives from government, regulatory agencies, academia, industry and scientific associations. Such an inclusive composition allows for transparent and open discussions on the aims and goals of the workshop. The practical training will be provided by IIVS on assays that are currently accepted at the OECD level, and will focus on the technical steps of the adopted in vitro protocols (highlighting the critical steps for data assessment), good laboratory practices, and finally the interpretation of results for regulatory purposes. Details on the concepts and organization of the practical trainings will be provided

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