Pharmacokinetics Simulations (v2.0)

Producer: COACS (Commercial and Academic Services), Ltd.

The primary objective of this package, originally developed at the Washington State University (USA) and reprogrammed by PCCAL International (UK), is to teach the basic principles of pharmacokinetics through computer simulations. Simulation of the plasma concentration-time profile is a valuable tool to understand the basic pharmokinetic principles and to appreciate the interplay of various pharmokinetic parameters. The program allows the student to evaluate the impact of changing one or more pharmokinetic parameters on the concentration-time profile of the drug. The program covers: IV bolus and oral drug administration; constant rate and intermittent IV infusions; single and multiple drug administration; linear and non-linear drug elimination; one- and two-compartment pharmokinetic models.


Medium: CD-ROM System requirements: Available in Windows and web/intranet versions. The Windows version (compatible with Windows 95/98/NT) is supplied on a CD-ROM installation disk and can be installed to a local hard disk or network drive; requires a PC with minimum 100 MHz Pentium processor, 8 MB RAM and a VGA monitor capable of displaying 16-bit colour at 640 x 480 resolution. The web version is supplied on a CD-ROM installation disk for installation to a web server and runs on PC clients only; requires a 200 MHz Pentium processor with 32 MB RAM and a Super VGA monitor capable of displaying 16-bit colour at 800 x 600 resolution; it is compatible with both Netscape Navigator 4.x and Internet Explorer 4 or better and requires Java and JavaScript to be enabled on browsers Price: £240.00 (excl. VAT at 17.5% for UK and EU orders, and £20.00 handling charge per order)